The fabrication and application of nanoparticle-based multifunctional composites (ナノ粒子を用いた多機能複合材料の創製と応用)【本文の要約】

信州大学(Shinshu university)博士（工学）この博士論文は、次の学術雑誌論文を一部に使用しています。／PHYSICA E-LOW-DIMENSIONAL SYSTEMS & NANOSTRUCTURES. 124:114249 (2020); doi:10.1016/j.physe.2020.114249. © 2020 Elsevier B.V. All rights reserved..／ENVIRONMENTAL TECHNOLOGY & INNOVATION. 21:101210 (2021); doi:10.1016/j.eti.2020.101210. © 2020 Elsevier B.V. All rights reserved..／MATERIALS CHARACTERIZATION. 172:110887 (2021); doi:10.1016/j.matchar.2021.110887. © 2021 Published by Elsevier Inc.ThesisLI XIAOJUAN. The fabrication and application of nanoparticle-based multifunctional composites (ナノ粒子を用いた多機能複合材料の創製と応用). 信州大学, 2021, 博士論文. 博士（工学）, 甲第745号, 令和03年03月20日授与.doctoral thesi

Optimized Hierarchical Power Oscillations Control for Distributed Generation Under Unbalanced Conditions

Control structures have critical influences on converter-interfaced distributed generations (DG) under unbalanced conditions. Most of previous works focus on suppressing active power oscillations and ripples of DC bus voltage. In this paper, the relationship between amplitudes of the active power oscillations and the reactive power oscillations are firstly deduced and the hierarchical control of DG is proposed to reduce power oscillations. The hierarchical control consists of primary and secondary levels. Current references are generated in primary control level and the active power oscillations can be suppressed by a dual current controller. Secondary control reduces the active power and reactive power oscillations simultaneously by optimal model aiming for minimum amplitudes of oscillations. Simulation results show that the proposed secondary control with less injecting negative-sequence current than traditional control methods can effectively limit both active power and reactive power oscillations.Comment: Accepted by Applied Energ

Forward-backward stochastic differential equations driven by G-Brownian motion under weakly coupling condition

In this paper, we obtain the existence and uniqueness theorem of $L^{p}$-solution for coupled forward-backward stochastic differential equations driven by G-Brownian motion (G-FBSDEs) with arbitrary $T$ under weakly coupling condition. Specially, the result for $p\in(1,2)$ is completely different from the one for $p\geq2$. Furthermore, by considering the dual linear FBSDE under a suitable reference probability, we establish the comparison theorem for G-FBSDEs under weakly coupling condition.Comment: 19 page

Combining Transfer of TTF-1 and Pax-8 Gene: a Potential Strategy to Promote Radioiodine Therapy of Thyroid Carcinoma

Cotransfer of TTF-1 and Pax-8 gene to tumor cells, resulting in the reexpression of iodide metabolism-associated proteins, such as sodium iodide symporter (NIS), thyroglobulin (Tg), thyroperoxidase (TPO), offers the possibility of radioiodine therapy to non-iodide-concentrating tumor because the expression of iodide metabolism-associated proteins in thyroid are mediated by the thyroid transcription factors TTF-1 and Pax-8. The human TTF-1 and Pax-8 gene were transducted into the human thyroid carcinoma (K1 and F133) cells by the recombinant adenovirus, AdTTF-1 and AdPax-8. Reexpression of NIS mRNA and protein, but not TPO and Tg mRNA and protein, was detected in AdTTF-1-infected F133 cells, following with increasing radioiodine uptake (6.1~7.4 times), scarcely iodide organification and rapid iodide efflux (t1/2≈8 min in vitro, t1/2≈4.7 h in vivo).
In contrast, all of the reexpression of NIS, TPO and Tg mRNA and proteins in F133 cells were induced by the synergetic effect of TTF-1 and Pax-8. AdTTF-1 and AdPax-8 coinfected K1 and F133 cells could effectively accumulate radioiodine (6.6-7.5 times) and obviously retarded radioiodine retention (t1/2≈25-30 min in vitro, t1/2≈12 h in vivo) (p<0.05).
Accordingly, the effect of radioiodine therapy of TTF-1 and Pax-8 cotransducted K1 and
F133 cells (21-25% survival rate in vitro) was better than that of TTF-1-transducted cells
(40% survival rate in vitro) (p<0.05). These results indicate that single TTF-1 gene transfer may have limited efficacy of radioiodine therapy because of rapid radioiodine efflux. The cotransduction of TTF-1 and Pax-8 gene, with resulting NIS-mediated radioiodine accumulation and TPO and Tg-mediated radioiodine organification and intracellular retention, may lead to effective radioiodine therapy of thyroid carcinoma

Failure prediction of ultra capacitor stack using fuzzy inference system

The failure of the ultracapacitor was significantly accelerated by elevated temperature or increased voltage. Because of the capacitance difference between the capacitor cells, after a number of deep charging/discharging cycles, the voltage difference between cells will be enlarged. This will accelerate the aging of the weak ultracapacitors and affect the output power. So, to improve stack reliability, a correct and timely failure prediction is essential. Based on diverse faults, a fuzzy rule-based inference system, which could approximate human reasoning, was considered. With this method we can reduce uncertainty, inconvenience and inefficiency resulting from the inherent factors. The simulate results under industrial application conditions are given to verify the method

Persistent Biomechanical Alterations After ACL Reconstruction Are Associated With Early Cartilage Matrix Changes Detected by Quantitative MR.

BackgroundThe effectiveness of anterior cruciate ligament (ACL) reconstruction in preventing early osteoarthritis is debated. Restoring the original biomechanics may potentially prevent degeneration, but apparent pathomechanisms have yet to be described. Newer quantitative magnetic resonance (qMR) imaging techniques, specifically T1ρ and T2, offer novel, noninvasive methods of visualizing and quantifying early cartilage degeneration.PurposeTo determine the tibiofemoral biomechanical alterations before and after ACL reconstruction using magnetic resonance imaging (MRI) and to evaluate the association between biomechanics and cartilage degeneration using T1ρ and T2.Study designCohort study; Level of evidence, 2.MethodsKnee MRIs of 51 individuals (mean age, 29.5 ± 8.4 years) with unilateral ACL injuries were obtained prior to surgery; 19 control subjects (mean age, 30.7 ± 5.3 years) were also scanned. Follow-up MRIs were obtained at 6 months and 1 year. Tibial position (TP), internal tibial rotation (ITR), and T1ρ and T2 were calculated using an in-house Matlab program. Student t tests, repeated measures, and regression models were used to compare differences between injured and uninjured sides, observe longitudinal changes, and evaluate correlations between TP, ITR, and T1ρ and T2.ResultsTP was significantly more anterior on the injured side at all time points (P < .001). ITR was significantly increased on the injured side prior to surgery (P = .033). At 1 year, a more anterior TP was associated with elevated T1ρ (P = .002) and T2 (P = .026) in the posterolateral tibia and with decreased T2 in the central lateral femur (P = .048); ITR was associated with increased T1ρ in the posteromedial femur (P = .009). ITR at 6 months was associated with increased T1ρ at 1 year in the posteromedial tibia (P = .029).ConclusionPersistent biomechanical alterations after ACL reconstruction are related to significant changes in cartilage T1ρ and T2 at 1 year postreconstruction. Longitudinal correlations between ITR and T1ρ suggest that these alterations may be indicative of future cartilage injury, leading to degeneration and osteoarthritis.Clinical relevanceNewer surgical techniques should be developed to eliminate the persistent anterior tibial translation commonly seen after ACL reconstruction. qMR will be a useful tool to evaluate the ability of these newer techniques to prevent cartilage changes

E-business Research in China over the Last Two Decades: a Bibliometric Analysis of Projects Granted by National Social Science Fund of China

The fast growth of electronic business activities in China during the last two decades has attracted significant attention from practice as well as academics in different countries. The purpose of this paper is to draw the basic outline of e-business research over the last two decades in China based on e-business research projects granted by National Social Science Fund of China from 1999 to 2017. Changes of the research on e-business over time, subject distribution, geographical distribution, active research institutions and high frequency words have been analyzed. The findings showed that the research subjects on e-business in China over last two decades could be classified into 6 categories: online consumer behavior, trust of e-business, internet business model innovation, rural electronic business, internet financial and macro issues related to e-business. The research on e-business has obtained the attention of researchers from different disciplines including management, economics, law, library, sociology, statistics, sports and journalism. The results have given a clear image of the academic investigation on e-business over the last two decades in China